Pulmonary vascular response to exercise in the dog.
نویسندگان
چکیده
The effects of exercise on the pulmonary circulation were studied in seven experiments on five dogs. Pulsatile pulmonary arterial flow and pressure and left atrial pressure were measured by chronically implanted transducers; pulmonary vascular input impedance, resistance, and hydraulic power were computed. The average effects of running on a treadmill at 6.5 mph, as compared with the resting state, were an increase in cardiac output from 2.59 liters/mm to 5.30 liters/min, a rise in mean pulmonary arterial pressure from 18 mm Hg to 28 mm Hg, and no consistent change in mean left atrial pressure. Pulmonary vascular resistance fell from 482 dyne sec cm" at rest to 372 dyne sec cmduring exercise. Characteristic input impedance rose from 147 dyne sec cm" at rest to 199 dyne sec cm" during exercise, and the oscillations of the impedance modulus with frequency decreased in magnitude. These changes were consistent with passive distention of the pulmonary vessels, decreasing the compliance of the large arteries and improving the impedance match between proximal and distal vessels.
منابع مشابه
Investigation of the Changes in Serum Intercellular and Vascular Adhesion Molecules (ICAM-1 and VCAM-1) and Nitric Oxide Levels in Response to Exercise Training and L-arginine Supplementation in Postmenopausal Hypertensive Women
متن کامل
Pulmonary Bulla in a Dog Secondary to Blastomycosis
Case description- A two-year-old intact Golden Retriever was affected with the 6-months previous history of blastomycosis and treatment was performed using fluconazole. Clinical findings- Cough, fever, nasal discharge, dry and harsh lung sounds with peripheral lymphadenopathy was observed. Emphysematous change and large pulmonary bulla was reported in computed tomography of the thorax. Treatm...
متن کاملThe Role of Anion Exchanger on Pulmonary Vascular Response to Sustained Alveolar Hypoxia in the Isolated Perfused Rabbit Lung
Background: Some respiratory diseases may induce alveolar hypoxia thereby hypoxic pulmonary vasoconstriction (HPV). However, the mechanisms of this physiologic phenomenon are not fully understood. This study was the first to investigate the role of anion exchanger in sustained HPV.Methods: Experiments were performed in the isolated perfused rabbit lung. After preparation, the lungs were divided...
متن کاملAbnormal bisubclavian trunk arising from the aortic arch determined by cadaver dissection of a native dog: A case report
Congenital anomalies of the great thoracic vessels have been reported in 20% of dogs and cats. In some cases, the vascular ring anomalies remain unrecognized throughout the lifetime of an animal. This report describes a case with an unusual vascular ring anomaly (VRA) that was detected during dissection on a cadaver of an approximately two-year-old male native mixed breed dog. No history of the...
متن کاملThree-Dimensional Color Doppler Ultrasonography Study of Normal Liver Vascular Pattern in Dog
Objective- To create three-dimensional model of the dog's liver vessels by using threedimensionalcolor Doppler ultrasonography which can be used for surgery planning,tumor detecting, transplantation, and other diagnostic or treatment project.Design- Descriptive studyAnimals- 6 mixed breed dog, 1.6-1.7 years old, 18-20 kg weightProcedures- The liver was found by two-dimensional scan initially th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Circulation research
دوره 29 6 شماره
صفحات -
تاریخ انتشار 1971